Asenapine: novel antipsychotic for treatment of bipolar I disorder
نویسندگان
چکیده
منابع مشابه
Asenapine for bipolar disorder
Asenapine (Saphris(®)) is an atypical antipsychotic drug which has been approved by the US Food and Drug Administration for the treatment of schizophrenia in adults, as well as the treatment of acute manic or mixed episodes of bipolar I in both adult and pediatric populations. Asenapine is a tetracyclic drug with antidopaminergic and antiserotonergic activity with a unique sublingual route of a...
متن کاملAsenapine for Bipolar Disorder in Older Adults
Methods: Participants, aged ≥60 years, were experiencing suboptimal response—defined as irritability, agitation, and mood lability or diminished ability to take care of basic personal needs as a result of their illness—to their current bipolar disorder medication. All patients had open-label, flexible-dose, sublingual asenapine added to their current medication for 12 weeks. Responses were eval...
متن کاملA Review of Asenapine in the Treatment of Bipolar Disorder
Bipolar disorder places a significant burden on the affected individuals, their family, healthcare systems and the overall economy. More treatment options are needed, especially those with better efficacy and tolerability. Asenapine is a second-generation antipsychotic approved in Europe (brand name Sycrest®) for the treatment of moderate-to-severe manic episodes associated with bipolar I disor...
متن کاملCost-effectiveness of asenapine in the treatment of bipolar I disorder patients with mixed episodes.
OBJECTIVE Around one-third of patients with bipolar I disorder (BD-I) experience mixed episodes, characterized by both mania and depression, which tend to be more difficult and costly to treat. Atypical antipsychotics are recommended for the treatment of mixed episodes, although evidence of their efficacy, tolerability, and cost in these patients is limited. This study evaluates, from a UK Nati...
متن کاملAsenapine: A Novel Hope in the Treatment of Schizophrenia and Manic and Mixed Episodes of Bipolar I Disorder
Schizophrenia is a globally prevalent, severe, chronic psychiatric disorder; leading edge research on the treatment of schizophrenia is carried out intensively both in our country and in the rest of the world (1-33). While impairing social functioning and occupational capacity, schizophrenia is an illness with a frequent occurrence of premature death due to its adverse effects on physical healt...
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ژورنال
عنوان ژورنال: Future Prescriber
سال: 2011
ISSN: 1468-9871
DOI: 10.1002/fps.84